I love 2d work very much.  I love it even more when both 3d is used to bring an extra upgrade in quality.  The other day I was checking out Mike Inel’s work.  I found this little video where Mike uses a type of mocap, rotoscoping and then tracing over the 3d work.  I’ll let you check out the process here below.

 

I noticed Otaking using a similiar process.  I think this helps take his 2d to the next level.

 

This should help you in your endeavors especially if you are not the best artist.    You could easily use Poser characters and trace over them in a 2d package.   Daz is free and you could do the same thing.  Go for it.  Make your own anime today.